I am fascinated by the question of how proteins are recognized as functional or aberrant/damaged/non-functional by cellular protein quality control mechanisms. How do cellular QC mechanisms make these decisions? What features of the proteins are recognized? And what features of the QC machinery provide them the ability to make the distinction? This becomes even more relevant in pathological conditions where damaged proteins are not efficiently removed resulting in accumulation of protein aggregates inside the cells.
Before coming to Cornell, I worked with Ron Kopito at Stanford University to understand protein quality control mechanisms at the Endoplasmic Reticulum. I did my PhD at UT Austin, where I studied the early steps critical in the biogenesis of the eukaryotic small ribosomal subunit and was advised by Arlen Johnson.
I am passionate about science and art. While science is what fills most of my time, art takes up a large part of my free time.
You can download my CV here.
You can see an up-to-date list of my publications here.